PRODUCT SRARCH
Welcome to use the web search system, you can enter the product name or product CAS number to search product . If you have any questions or sugesstions, please contact us.
|
Cas No. |
Product name |
131740-09-5 |
Flavopiridol HCl |
more... |
Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol ... |
1397219-81-6 |
BS181 |
more... |
BS-181 is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9 |
582315-72-8 |
BMS265246 |
more... |
BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM. It is 25-fold more selective for CDK1/2 than CDK4 |
173529-46-9 |
HMN-214 |
more... |
HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation of Plk1. |
1035555-63-5 |
TAK733 |
more... |
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1. |
871700-17-3 |
Trametinib (GSK1120212) |
more... |
Trametinib (GSK1120212) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. Phase 3. |
209410-46-8 |
VX745 |
more... |
VX-745 is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ. |
606143-52-6 |
Selumetinib (AZD6244) |
more... |
Selumetinib (AZD6244) is a potent, highly selective MEK1 inhibitor with IC50 of 14 nM, also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, E... |
152121-47-6 |
SB203580 |
more... |
SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. |
1221485-83-1 |
Skepinone-L |
more... |
Skepinone-L is a selective p38α-MAPK inhibitor with IC50 of 5 nM. |
|